Movies
* Max Headroom (1985): His breakout role, playing the titular computer-generated character, a sassy and witty artificial intelligence.
* The Fly (1986): He plays the best friend of Seth Brundle (Jeff Goldblum) in this classic body horror film.
* Honey, I Shrunk the Kids (1989): He voices the voice-activated robot, "Gizmo."
* The Dark Half (1993): He portrays the antagonist, Thad Beaumont, in this Stephen King adaptation.
* The Stand (1994): He plays the character of "The Trashcan Man" in this adaptation of Stephen King's novel.
* Plan 9 from Outer Space (1995): He plays the character of "The Old Man" in this mockumentary about the infamous Ed Wood film.
* The Faculty (1998): He portrays the character of Mr. Furlong, a teacher who is actually an alien.
* Night of the Living Dead 3D (1990): He plays the role of "Johnny," a character trying to survive the zombie apocalypse.
Television
* Max Headroom (1987-1988): He reprised his role as Max Headroom in this short-lived but influential television series.
* Babylon 5 (1994-1998): He played the memorable recurring role of "Londo Mollari," the ambitious and cunning ambassador of the Centauri Republic.
* The Twilight Zone (1985-1989): He appeared in an episode titled "The Toys of Caliban" as "Caliban."
* Star Trek: The Next Generation (1987-1994): He played the character "The Traveler" in two episodes.
* Doctor Who (2011): He played the role of "The Prisoner" in the episode "The Impossible Astronaut."
* The Librarians (2014-2018): He played the recurring character "Professor Moriarty" in this series.
* Warehouse 13 (2009-2014): He appeared in an episode of this show as "The Man in Black," a mysterious figure associated with the Warehouse.
* Eureka (2006-2012): He played the character "Dr. Victor Helios" in the series finale of this show.
* The Expanse (2015-2022): He played the recurring role of "Camina Drummer" in this science fiction series.
* The Orville (2017-present): He plays the character "Klyden" in this sci-fi comedy series.
This is just a selection of Matt Frewer's extensive and diverse career. He has also appeared in numerous other television shows, including "The Simpsons," "Futurama," and "Scrubs." He continues to work in the industry, demonstrating his versatility and talent.