Television
* La Reina del Sur (2011-2019) as Teresa Mendoza
* El Señor de los Cielos (2013-2021) as Monica "La Güera"
* The Last Ship (2014-2018) as Dr. Andrea "Andy" Brownell
* Queen of the South (2016-2021) as Teresa Mendoza
* The Gifted (2017-2019) as Dr. Clarice Fong
* The Oath (2018) as Maria
* The Sinner (2019) as Detective Heather Hall
* The Purge (2018-2020) as Esme
Films
* Man on Fire (2004) as Samantha "Sam" Ramon
* The Twilight Saga: New Moon (2009) as Angela Weber
* The Twilight Saga: Eclipse (2010) as Angela Weber
* The Twilight Saga: Breaking Dawn – Part 1 (2011) as Angela Weber
* The Twilight Saga: Breaking Dawn – Part 2 (2012) as Angela Weber
* After Earth (2013) as Dr. Ray
* The Hunger Games: Mockingjay – Part 2 (2015) as Commander Lyme
* The Maze Runner: The Death Cure (2018) as Brenda
* The Tomorrow War (2021) as Cristina
This is not an exhaustive list, and she has appeared in several other projects as well. Her career has spanned over two decades, and she has been recognized for her talent and versatility as an actress.