* John James Ingalls (1833-1900) - U.S. Senator from Kansas (1873-1891) and Kansas Supreme Court Justice (1862-1865).
* Thomas Sterling (1851-1930) - U.S. Senator from South Dakota (1913-1925) and Governor of South Dakota (1901-1905).
* Peter Norbeck (1870–1936) - Politician and the 14th Governor of South Dakota (1917–1921) and U.S. Senator from South Dakota (1921–1936).
* Gladys Pyle (1890-1980) - The first female governor of South Dakota (1953-1955) and the first female governor of any U.S. state to be elected to a four-year term.