The setting of "The Man with the Twisted Lip" is primarily:
* London, England: The story is set in Victorian London, specifically around the areas of Baker Street (where Sherlock Holmes resides), the "coffin factory" where Neville St. Clair works, and various London streets where Holmes and Watson conduct their investigations.
* The "coffin factory": This is a key location, described as a small, dingy establishment in a back street. It is where St. Clair is believed to be employed, and where the story unfolds.
Specific locations within the story include:
* 221B Baker Street: Sherlock Holmes's famous residence, where much of the investigation takes place.
* The "coffin factory" itself: This is where the protagonist, Neville St. Clair, works.
* Various London streets: The investigation takes Holmes and Watson to different parts of London, including a public house, a park, and a pawnshop.
Overall, the setting of "The Man with the Twisted Lip" is the familiar and atmospheric London of Victorian times, with its bustling streets, dark secrets, and a distinct social hierarchy.