- Bulbasaur (Found in the Kanto region)
- Ivysaur (Evolved from Bulbasaur)
- Venusaur (Evolved from Ivysaur)
- Charmander (Found in the Kanto region)
- Charmeleon (Evolved from Charmander)
- Charizard (Evolved from Charmeleon)
- Squirtle (Found in the Kanto region)
- Wartortle (Evolved from Squirtle)
- Blastoise (Evolved from Wartortle)
- Mewtwo (Found in the Cerulean Cave)
- Mew (Found in the Safari Zone)
- Articuno (Found in the Seafoam Islands)
- Zapdos (Found in the Power Plant)
- Moltres (Found in Mt. Ember)
- Ditto (Found in the Pokémon Mansion)
- Lapras (Found in the Safari Zone)
- Hitmonlee (Found in the Fighting Dojo)
- Hitmonchan (Found in the Fighting Dojo)
- Kabuto (Found in the Safari Zone)
- Kabutops (Evolved from Kabuto)
- Omanyte (Found in the Safari Zone)
- Omastar (Evolved from Omanyte)
- Porygon (Found in the Silph Co. Building)
- Scyther (Found in the Safari Zone)
- Scizor (Evolved from Scyther with Metal Coat)
- Heracross (Found in the Johto region)
- Snorelax (Found on Route 12)