Main Series Games:
* Resident Evil 2 (1998): His first appearance, a rookie cop fighting the outbreak in Raccoon City.
* Resident Evil 4 (2005): A major turning point for Leon, now a special agent on a mission to rescue the President's daughter.
* Resident Evil 6 (2012): Leon is again a special agent, facing a global bio-weapon threat.
Other Games:
* Resident Evil: Dead Aim (2003): Leon and a U.S. Marshal investigate a bio-terror incident on a cruise ship.
* Resident Evil: The Mercenaries 3D (2011): A spin-off featuring Leon in a series of challenging combat scenarios.
* Resident Evil Revelations 2 (2015): Leon makes a cameo appearance, helping Claire Redfield during the game's story.
* Resident Evil: Umbrella Corps (2016): Leon appears as a playable character in the multiplayer spin-off.
* Resident Evil Village (2021): Leon has a brief, but significant, role in the story, appearing as a secret agent assisting Chris Redfield.
Remakes and Remaster:
* Resident Evil 2 Remake (2019): Leon's story in Raccoon City is given a modern update with improved visuals and gameplay.
* Resident Evil 4 Remake (2023): Leon's journey to rescue the President's daughter gets a complete overhaul.
Total: Leon appears in 8 main series games, along with several other spin-offs and remakes, making him one of the most prominent characters in the Resident Evil franchise.