The scene you are likely referring to occurs when Ponyboy, Johnny, and Dallas are hiding out in an abandoned church after killing Bob Sheldon. Jerry, a young boy they encounter in the church, makes the statement that they were sent from heaven to save him and the other children in the church.
Ponyboy doesn't respond verbally to Jerry's statement. He's likely too preoccupied with the situation, the fear of being caught, and the weight of what they've done. He's also focused on caring for Johnny, who is badly injured.
Instead of a verbal response, Ponyboy shows his agreement with Jerry's statement through his actions. He helps Jerry and the other children escape the church, proving that he does care about them and wants to help them.
The significance of this scene lies in the contrast between Jerry's innocent view of their actions and the reality of the situation. Ponyboy and his friends are on the run from the law, their actions have consequences, and they are struggling with their own internal turmoil.
Ponyboy's silence in this scene highlights the complexity of his emotions and the difficult situation he finds himself in.