* If you mean cards that exist in the real world: Yes, there are real Yu-Gi-Oh! cards! The Trading Card Game (TCG) is a physical card game with thousands of different cards.
* If you mean cards based on the anime/manga: Many Yu-Gi-Oh! cards are inspired by the anime and manga, but not all of them. There are some cards that are unique to the show, and some cards in the TCG have different effects or names compared to their anime counterparts.
So, it's important to be specific about what you're looking for!
Can you tell me more about what kind of "real Yu-Gi-Oh card" you're interested in?