Main Story:
* Head to Ecruteak City: This is your next destination, where you'll encounter the legendary Pokemon, Entei, Raikou, or Suicune depending on your game version (HeartGold has Entei).
* Investigate the Ruins of Alph: These ruins are located near Ecruteak City and hold a key to uncovering the mystery behind the legendary Pokemon and their connection to the mythical Pokemon, Ho-Oh.
* Continue to the 7th Gym: After uncovering some mysteries in Ecruteak, you'll eventually be able to challenge the 7th Gym Leader, Clair in Blackthorn City.
Side Quests:
* Complete the "I Choose You!" Event: This event is triggered by visiting the Goldenrod City Radio Tower and listening to the news. It features the original 151 Pokemon and allows you to catch a new Pokemon in the wild.
* Train your Pokemon: This is a good time to level up your Pokemon and learn new moves to prepare for the challenging Gym battles and upcoming adventures.
* Find the Missing Trainer: You can find a missing trainer who is searching for his lost Pokemon, allowing you to help him find it.
* Collect Trainer Cards: Keep challenging other trainers to collect their Trainer Cards, and show off your skills and collection.
* Catch Pokemon: Explore the different regions you've unlocked and capture new Pokemon to expand your team and learn about their strengths and weaknesses.
Tips:
* Make sure your team is well-prepared: Gyms and wild Pokemon become increasingly stronger, so you'll need a diverse team with strong moves and strategies.
* Experiment with new Pokemon: Try out some new Pokemon you've caught to see if they fit your team's style.
* Explore the regions: Don't forget to explore the different regions, as there are many hidden secrets and items to discover.
Remember, the game is yours to enjoy! Do what you feel like doing, and have fun!