* Elena Gilbert: He's her biological uncle, being the brother of her mother, Miranda Sommers.
* Jeremy Gilbert: He's also Jeremy's uncle, as John is Jeremy and Elena's father's brother.
However, it's important to note that John Gilbert was not a very present or good uncle in the series. He was often absent, and when he was around, he was often focused on his own agenda and keeping secrets. He ultimately died in the second season, leaving Elena and Jeremy without their uncle.
Other characters who could be considered "uncles" in the show include:
* Alaric Saltzman: While he's not related to Elena and Jeremy by blood, he is their guardian and acts as a father figure, making him a kind of "uncle" in a way.
* Klaus Mikaelson: Klaus is the father of the hybrid, Caroline Forbes, and therefore could be considered an uncle to her.
Ultimately, the term "uncle" is a bit fluid in the context of *The Vampire Diaries*. While John Gilbert is the only character who is explicitly referred to as an uncle, other characters, like Alaric and Klaus, fill similar roles in the lives of the main characters.