Here's the breakdown:
* The painting: The portrait is called "Pope Leo X with Cardinals Giulio de' Medici and Luigi de' Rossi" and is considered a masterpiece of the High Renaissance.
* The cardinals: The cardinals depicted are Giulio de' Medici (later Pope Clement VII) and Luigi de' Rossi.
* The composition: Raphael's painting was actually composed by combining multiple portraits of the individuals, painted at different times. The Pope's portrait was done separately, as were the cardinals'.
So, while the final result makes it seem like they are all posing together, they were not actually in the same room at the same time. This was a common practice for Renaissance portrait artists, allowing for more flexibility and control over the final composition.