- John Candy as Buck Russell
- Jean Louisa Kelly as Tia Russell
- Macaulay Culkin as Miles Russell
- Gaby Hoffman as Maizy Russell
- Amy Madigan as Cindy Russell
- Kevin Meaney as Chan Mercer
- Laurie Metcalf as Marcie Dahlgren-Frost
- Jay Underwood as Bug Hall
- Suzanne Snyder as Anita
- Garrett M. Brown as Mr. Hatfield
- Elaine Bromka as Mrs. Hatfield
- Brian Doyle-Murray as Uncle Frank