* Francesca Bertini: Italian silent film actress who was one of the most popular stars of the 1910s and 1920s.
* Francesca da Rimini: Italian noblewoman who is the subject of a famous tragedy by Dante Alighieri.
* Francesca Eastwood: American actress, model, and social media influencer, daughter of actor Clint Eastwood.
* Francesca Hayward: British ballet dancer who is a principal dancer with The Royal Ballet.
* Francesca Neri: Italian actress known for her roles in films such as "Live Flesh" and "The Last Kiss."
* Francesca Schiavone: Italian tennis player who won the French Open in 2010.
* Francesca Woodman: American photographer known for her black-and-white self-portraits.