* Michael Caine as Jon Lansdale
* Andrea Marcovicci as Anna Lansdale
* Freida Pinto as Dr. Amanda Fallon
* William Devane as Dr. Jack Hallam
* Sylvester Stallone as the Hand (uncredited)
Please note that Sylvester Stallone is only credited as "The Hand" in the film and not by his real name. It's a fun fact, though, that the iconic action star played such a bizarre role in this thriller.