All Five Films:
* Johnny Depp as Captain Jack Sparrow
* Geoffrey Rush as Captain Hector Barbossa
Four Films:
* Orlando Bloom as Will Turner
* Keira Knightley as Elizabeth Swann
Three Films:
* Naomie Harris as Tia Dalma/Calypso (Curse of the Black Pearl, Dead Man's Chest, At World's End)
* Kevin McNally as Joshamee Gibbs (Curse of the Black Pearl, Dead Man's Chest, At World's End)
Two Films:
* Jack Davenport as James Norrington (Curse of the Black Pearl, Dead Man's Chest)
* Lee Arenberg as Pintel (Curse of the Black Pearl, Dead Man's Chest)
* Mackenzie Crook as Ragetti (Curse of the Black Pearl, Dead Man's Chest)
* Jonathan Pryce as Governor Weatherby Swann (Curse of the Black Pearl, Dead Man's Chest)
* Stellan Skarsgård as Captain Bill "Bootstrap Bill" Turner (Dead Man's Chest, At World's End)
One Film:
* Bill Nighy as Davy Jones (Dead Man's Chest, At World's End)
* Sam Claflin as Phillip Swift (On Stranger Tides)
* Penélope Cruz as Angelica (On Stranger Tides)
* Ian McShane as Blackbeard (On Stranger Tides)
* Javier Bardem as Captain Salazar (Dead Men Tell No Tales)
* Kaya Scodelario as Carina Smyth (Dead Men Tell No Tales)
Recurring Characters with Different Actors
* The character of Jack Sparrow was briefly played by Keith Richards in At World's End.
* The character of Blackbeard was briefly played by David Bailie in Curse of the Black Pearl.
This list only includes the main actors in the Pirates of the Caribbean series. There are many other supporting actors and characters.
Let me know if you'd like to know more about the characters or the films!