Option 1: The Opportunist:
* Wile E. might see Scooby Doo as a new, bigger, and potentially tastier target. He'd try to distract Scooby with a trap, hoping to catch the Great Dane and then use him as bait to lure the Road Runner.
Option 2: The Confused and Frustrated:
* Wile E. might be confused by the whole situation. Scooby Doo is a completely different kind of prey, and his usual tactics might not work. He might try to reason with Scooby, thinking he's just helping him catch the Road Runner.
Option 3: The Jealous Competitor:
* Wile E. might be envious of Scooby's success. He might try to sabotage Scooby's chase, either by tripping him up or by using his Acme gadgets to confuse him.
Option 4: The Team-Up:
* Wile E. could realize that they're both chasing the same quarry and team up with Scooby Doo. However, this would probably lead to more chaos and mishaps, as their approaches to catching the Road Runner are wildly different.
The most likely outcome:
* No matter what Wile E. does, it's going to be a hilarious disaster. He's likely to end up more frustrated and injured than ever, while Scooby Doo will probably be more interested in Scooby Snacks than catching the Road Runner.
The beauty of this scenario is that it could go in countless directions, depending on the writers and animators' creativity!