The most famous puppeteer to play Miss Piggy is Frank Oz, who brought her to life for the majority of her appearances from 1976 until 2011. However, several other puppeteers have also played her, including Bill Barretta and Dave Goelz.
It's important to remember that while the puppeteers control the physical movements of the character, it's the voice and personality of Miss Piggy that really bring her to life, which is attributed to the iconic voice actress Caroll Spinney.