- John Lennon: The legendary musician, who was born in Liverpool, moved to Wirral with his family when he was a child. He lived in several different houses in the area, including Mendips, a large Victorian house in Menlove Avenue, and Quarry Bank High School, where he formed his first band, The Quarrymen.
- Paul McCartney: Another member of The Beatles, Paul McCartney, also lived in Wirral for a time. He moved to the area with his family when he was young and attended the same school as John Lennon, Quarry Bank High School.
- George Harrison: The third Beatle, George Harrison, lived in Wirral for a brief period when he was a child. His family lived in a house on the banks of the River Mersey in the village of Woolton.
- Ringo Starr: The fourth Beatle, Ringo Starr, also lived in Wirral for a time. He grew up in the Dingle area of Liverpool, but he moved to Wirral with his family when he was a teenager.
- Cilla Black: The popular singer and TV presenter, Cilla Black, was born in Liverpool and moved to Wirral with her family when she was a young child. She grew up in the town of West Kirby and attended the local grammar school.
- Jimmy Tarbuck: The comedian and entertainer, Jimmy Tarbuck, was born in Liverpool and moved to Wirral with his family when he was a child. He grew up in the town of Moreton and attended the local grammar school.
- Kenny Dalglish: The Scottish football player and manager, Kenny Dalglish, moved to Wirral in 1977 when he signed for Liverpool FC. He lived in the area for many years during his playing and managerial career with the club.