It seems you're asking about Oda Nobunaga, a famous Japanese warlord of the Sengoku period.
Oda Nobunaga did not die of natural causes. He was assassinated on June 21, 1582, by his trusted general Akechi Mitsuhide at the Honnō-ji Temple in Kyoto.
There is no record of a person named Oda Nobuhiro, so it's likely a misspelling.