* Marissa Jaret Winokur as Tracy Turnblad
* Harvey Fierstein as Edna Turnblad
* Dick Latessa as Wilbur Turnblad
* Matthew Morrison as Link Larkin
* Kerry Butler as Penny Pingleton
* Laura Bell Bundy as Amber Von Tussle
* Zac Efron as Corny Collins
* Ruth Brown as Motormouth Maybelle
* Mary Bond Davis as Velma Von Tussle
* Corey Reynolds as Seaweed Stubbs
* Shayna Steele as Little Inez
* Clarke Thorell as Prudy Pingleton
* Jerry O'Boyle as Mr. Spritzer
* Jackie Hoffman as Matron "Mama" Morton
* Michael McKean as Harriman F. Spritzer