- Thomas: The protagonist, a teenage boy who is sent to the Maze with no memories of his past.
- Teresa: A teenage girl who is also sent to the Maze, and who has some knowledge of the past.
- Minho: A teenage boy who is the leader of the Gladers, a group of boys who have been trapped in the Maze for several years.
- Newt: A teenage boy who is the second-in-command of the Gladers.
- Alby: A teenage boy who is the oldest of the Gladers.
- Chuck: A young boy who is the newest arrival in the Maze.
- Gally: A teenage boy who is antagonistic towards Thomas and the other new arrivals.