1. William: The first murder in the novel is that of Victor Frankenstein's younger brother, William. He is murdered by the creature that Victor has created.
2. Justine Moritz: The second murder is that of Justine Moritz, a servant in Victor's household. She is falsely accused of murdering William and executed.
3. Henry Clerval: The third murder is that of Henry Clerval, Victor's best friend. He is murdered by the creature while visiting Victor in Geneva.
4. Elizabeth Lavenza: The fourth and final murder is that of Elizabeth Lavenza, Victor's wife. She is murdered by the creature on her wedding night.