Television
* Switched at Birth (2011-2017): Marano played the role of Bay Kennish, one of the main characters and a deaf teenager who was switched at birth. This was a critically acclaimed series on ABC Family (now Freeform) that showcased Marano's acting range and earned her a Teen Choice Award.
* The Young and the Restless (2007-2009): Marano began her career on this long-running soap opera as the character of Cassie Newman.
* The Following (2013-2015): She played a recurring role as Lily, a student of Joe Carroll, the main antagonist.
* Grey's Anatomy (2015): She appeared as a patient with a complex medical condition.
* The Resident (2018): Marano appeared in the episode "Fear" as a patient.
* The Haunting of Hill House (2018): She voiced the character of Young Shirley in this popular Netflix horror series.
* The Walking Dead (2019): She played the role of Judith Grimes, the daughter of Rick Grimes, in the season 9 episode "Adaptation."
* The Flash (2020): Marano appeared as the character of Josie Totah in an episode.
* The Magicians (2016-2020): She played the role of Alice Quinn in this popular SyFy series.
* Walker (2021): Marano appeared as Denise in the "Ghosts" episode.
* The Outpost (2018-2021): She played the character of Nala in this Syfy series.
Film
* The Clique (2008): Marano had a starring role as Massie Block.
* The Secret Life of the American Teenager (2008): This was a direct-to-DVD film based on the TV series.
* Mean Girls 2 (2011): Marano starred as Jo, a new student at North Shore High.
* The Perfect Catch (2013): She played a lead role as a girl who has a crush on a baseball player.
* The After Party (2014): Marano starred in this romantic comedy film.
This is not an exhaustive list, but it highlights the breadth of projects Vanessa Marano has been involved in. She is a versatile actress with a strong career in both television and film.