Did Lauren ondecker had a screaming part in Spider-Man 3?

You're likely thinking of Bryce Dallas Howard, who played Gwen Stacy in Spider-Man 3. She does have a screaming scene in the movie, but it's not particularly notable as a major "screaming part."

There's no record of an actress named "Lauren Ondedecker" involved in Spider-Man 3 or any other major film. It's possible you're misremembering the name or that you're thinking of a scene with a different actress.