The main cast of *Ball of Fire* (1941) included:
* Gary Cooper as Professor Bertram Potts
* Barbara Stanwyck as Sugarpuss O'Shea
* Oscar Homolka as Professor Otto Ludwig
* Dana Andrews as Joe Lilac
* Henry Travers as Professor Theodore "Ted" Mallory
* S.Z. Sakall as Professor Joseph "Joe" Swallow
* Tom Conway as Professor Montague "Monty" Stratton
* Darryl Hickman as Professor Bertram Potts Jr.
* Kathleen Lockhart as Professor Amanda "Amy" L.
Richard Basehart was a well-known actor, but his career began in the 1940s. He starred in films like *The Thing from Another World* (1951), *The Left Hand of God* (1955) and played Captain Nemo in the television series *Voyage to the Bottom of the Sea*.