1. Iago says mockingly to Roderigo, "Thou told'st me thou didst hold him in thy hate." This is ironic because Roderigo seeks revenge on Othello through Iago’s manipulation.
2. Othello remarks to Desdemona, "If it were now to die,
T’were now to be most happy; for, I fear,
My soul hath her content so absolute
That not another comfort like to this
Succeeds in unknown fate." Othello implies he could never achieve greater happiness than he has with Desdemona, but the audience knowns this bliss will not last due to Iago’s sinister plans.