What is the moral lesson of Cloudy with a Chance Meatballs?

Be responsible with scientific discoveries. Flint Lockwood's invention, the FLDSMDFR, was intended to solve the town's food shortage, but it quickly spirals out of control. Flint's lack of responsibility and accountability for his actions leads to the town's destruction.

Don't take things for granted. Flint's town was used to eating regular, natural food. But once they had the FLDSMDFR, they took the food for granted and started to demand more and more. This led to the machine malfunctioning and causing chaos.

Be careful what you wish for. Flint's wish came true, but not in the way he expected. He wanted to solve the town's food shortage, but he ended up creating a dangerous situation.