The show featured a young boy named Michael "Mike" Taylor (played by Paul Provenza), who is raised by two very different men who both claim to be his father:
* Dr. Norman "Norm" Cooper (played by Greg Evigan), a successful and wealthy physician.
* "Mac" Taylor (played by Stamos), a charming but irresponsible musician.
The show focused on the comedic chaos and heartwarming moments that arose from their contrasting personalities and parenting styles.