* Aissa Wayne (born 1932) - His daughter from his first marriage to Josephine Alicia Saenz.
* Patrick Wayne (born 1939) - His son from his first marriage to Josephine Alicia Saenz.
* Michael Wayne (born 1941) - His son from his first marriage to Josephine Alicia Saenz.
* Tony Wayne (born 1942) - His son from his second marriage to Esperanza "Pita" Baur.
* Ethan Wayne (born 1950) - His son from his second marriage to Esperanza "Pita" Baur.
* Melinda Wayne (born 1956) - His daughter from his third marriage to Pilar Palette.
* Marisa Wayne (born 1960) - His daughter from his third marriage to Pilar Palette.