The names of Ne-Yo's children are not mentioned in the lyrics of "So Sick." However, the song does mention that Ne-Yo has a "little girl" and a "little boy." It is possible that these lyrics are about Ne-Yo's children.
The lyrics of "So Sick" describe a man who is in love with a woman. He is so in love with her that he feels "so sick." He talks about how he can't sleep or eat, and how he just wants to be with her. The song is about the power of love and how it can make us feel sick, but also happy and complete.