Carlos Santana is a legendary guitarist and musician known for his Latin-infused rock music. He has collaborated with various artists throughout his career, but there hasn't been any mention of a collaboration with Ariana Grande specifically.
Ariana Grande, on the other hand, is a successful pop singer and songwriter. She has also collaborated with numerous artists, but a collaboration with Carlos Santana has not been publicly discussed or hinted at by either party.
Music collaborations often depend on various factors such as scheduling, musical compatibility, and creative alignment. Until there is an official announcement from the artists or their respective teams, it remains speculative whether a Carlos Santana and Ariana Grande song will materialize.