- Euphonium: The euphonium is a brass instrument that is similar to the trombone, but it is pitched in B♭. A trombone mouthpiece can be used on a euphonium to produce a different sound.
- Tuba: The tuba is the lowest-pitched brass instrument. A trombone mouthpiece can be used on a tuba to produce a higher-pitched sound.
- Bass trombone: The bass trombone is a larger version of the trombone that is pitched in B♭. A trombone mouthpiece can be used on a bass trombone to produce a different sound.
- Cimbasso: The cimbasso is a brass instrument that is similar to the bass trombone, but it is pitched in F. A trombone mouthpiece can be used on a cimbasso to produce a higher-pitched sound.
- Serpent: The serpent is a historical brass instrument that has a winding shape. A trombone mouthpiece can be used on a serpent to produce a different sound.