Following their victory, Little Mix signed with Syco Music and released their debut single "Wings," which debuted at number one on the UK Singles Chart and was certified platinum. Their debut album DNA, released in November 2012, also reached number one in the UK and was certified double platinum. The album produced two more singles, "DNA" and "Change Your Life," both of which reached the top ten in the UK.
In 2013, Little Mix released their second album, Salute. The album debuted at number four on the UK Albums Chart and was certified gold. It produced four singles, including the lead single "Move," which reached number three on the UK Singles Chart. The following year, the group released their third album, Get Weird. The album debuted at number two on the UK Albums Chart and was certified platinum. It produced four successful singles, including the lead single "Black Magic," which reached number one in the UK.
In 2016, Little Mix released their fourth album, Glory Days. The album debuted at number one on the UK Albums Chart and was certified double platinum. It produced several hit singles, including "Shout Out to My Ex," which reached number one in the UK. The album was also nominated for British Album of the Year at the 2017 Brit Awards.
In 2018, Little Mix released their fifth album, LM5. The album debuted at number three on the UK Albums Chart and was certified gold. It produced several hit singles, including "Woman Like Me," which reached number two in the UK.
In 2020, Little Mix released their sixth album, Confetti. The album debuted at number two on the UK Albums Chart and was certified silver. It produced several hit singles, including the lead single "Break Up Song," which reached number two in the UK.
In December 2020, Jesy Nelson announced her departure from Little Mix, citing mental health reasons. The remaining three members of the group continued as a trio and released their seventh album, Between Us, in 2021.
Throughout their career, Little Mix has sold over 60 million records worldwide. They have won numerous awards, including four Brit Awards, two MTV Europe Music Awards, and one American Music Award. In 2021, they were listed as the 20th-most successful UK Singles Chart artists of all time, and in 2022, they became the first girl group to have five number one albums on the UK Albums Chart.