Turn the volume on the amp all the way down to zero. This will ensure that no damage is done when it is turned on.
Plug your guitar or other instrument into the amp by plugging a guitar cable into the instrument, with the other end plugged into the input on the amp.
Check the power switch to ensure that it is off.
Plug the power cable in the back of the amp either directly into the wall, or into a surge protector, which is then plugged into the wall.
Turn the power on at the surge protector if you are using one. Turn the power on the amp by flipping the power switch to the "on" position. It will often glow red when it is powered.
Turn the volume up to the desired level.