* Creative differences: The band members had different ideas about the direction of the band's music, and this led to conflict. Axl Rose wanted to take the band in a more experimental direction, while Slash and Duff McKagan wanted to stick to the band's heavier roots.
* Substance abuse: Guns N' Roses were known for their partying and drug use, and this took a toll on the band's relationships. Axl Rose's heroin addiction also made it difficult for him to work productively with the other band members.
* Management issues: Guns N' Roses were plagued by management problems throughout their career. The band's manager, Alan Niven, was accused of stealing from the band, and they eventually fired him. This led to legal problems that further disrupted the band.
* Personal tensions: There were also personal tensions between the band members that contributed to their split. Axl Rose was known for being difficult to work with, and he clashed with many of the other band members.
All of these factors combined to lead to the breakup of Guns N' Roses in 1993. However, the band reunited in 2016 for a series of reunion concerts.