Comedies:
* Scary Movie 3 (2003) - as George
* Scary Movie 4 (2006) - as George
* Red, White & Blue (2010) - as Tommy
* The Legend of Awesomest Maximus (2013) - as The Awesomest Maximus
* The Clapper (2017) - as Eddie
Dramas:
* The Informant! (2009) - as Mark Whitacre
* The Other Guys (2010) - as Roger
* The Legend of Awesomest Maximus (2013) - as The Awesomest Maximus
* The Clapper (2017) - as Eddie
Adult Films:
* The Devil's Rejects (2005) - as Otis Driftwood
* The House of the Devil (2009) - as Max
* The Legend of Awesomest Maximus (2013) - as The Awesomest Maximus
Other:
* The Tonight Show with Jay Leno (TV Series, 2004-2014) - as himself
* The Soup (TV Series, 2004-2015) - as himself
This is not an exhaustive list, but it includes some of his most well-known and critically acclaimed performances.
It's important to note that Simon Rex has been involved in a wide range of projects, and his career has been marked by both commercial success and critical acclaim.