Movies:
* The Adventures of Rocky & Bullwinkle (2000) - as Karen Sympathy
* Whatever It Takes (2000) - as Tracy
* The Longest Yard (2005) - as Brenda
* Employee of the Month (2006) - as Jill
* The Perfect Man (2005) - as Jennifer
* The Devil Wears Prada (2006) - as Irwin's assistant
* The House Bunny (2008) - as Shelley
* The Ugly Truth (2009) - as Mindy
* The Other Guys (2010) - as Sheila
* The Guilt Trip (2012) - as Karen
* The Heat (2013) - as Gina
* The Internship (2013) - as Dana
* Don't Worry, He Won't Get Far on Foot (2018) - as Cindy
Television:
* The Drew Carey Show (1995-2004) - as Mimi Bobeck
* King of the Hill (2001-2010) - as Peggy Hill (voice)
* The Suite Life of Zack & Cody (2006-2008) - as Ms. Tutweiller
* Curb Your Enthusiasm (2007) - as Janet
* Community (2011-2015) - as Shirley Bennet
* Supernatural (2016) - as The Darkness (voice)
* The Librarians (2014-2018) - as Eve Baird
* The Goldbergs (2014-2023) - as Beverly Goldberg
* Young Sheldon (2017-present) - as Beverly Hofstadter (voice)
* The Unicorn (2019-2021) - as Erin
* The Afterparty (2022) - as Detective Danner
This is not an exhaustive list, but it covers some of her most popular and notable projects.