Movies:
* 1999: "Second Name" (Second Nombre)
* 2002: "Lucía y el sexo"
* 2002: "Hable con ella" (Talk to Her) - Won Goya Award for Best New Actress
* 2003: "The Dancer Upstairs"
* 2004: "Spanglish"
* 2005: "The Last Days" (Los últimos días)
* 2006: "The Secret Life of Words"
* 2008: "The Reaping"
* 2009: "Rage"
* 2010: "Catfight"
* 2011: "The Coldest Game"
* 2011: "Without Men"
* 2013: "The Counselor"
* 2013: "A Day in the Life"
* 2014: "The Seventh Son"
* 2015: "A Perfect Day"
* 2016: "The Last Face"
* 2016: "The Promise"
* 2017: "The Light of the Moon"
* 2017: "The Etruscan Smile"
* 2019: "The Mule"
* 2020: "The 355"
* 2021: "The Birthday Cake"
* 2022: "The Enforcer"
* 2023: "A Haunting in Venice"
Television:
* 2003-2004: "Second Name" (TV series) - Also starred in the film adaptation
* 2005-2007: "The Division" (TV series)
* 2009-2011: "The Cleaner" (TV series)
* 2011-2014: "Touch" (TV series)
* 2015: "The Messengers" (TV series)
* 2017-2018: "Jane the Virgin" (TV series)
* 2019-2020: "Now Apocalypse" (TV series)
* 2020-present: "The Purge" (TV series)
* 2021-present: "The Lord of the Rings: The Rings of Power" (TV series)
This list is not exhaustive but includes her most notable projects.
Note: Please note that dates for some projects might vary depending on the region's release.