* Ryan Phillippe as John "Doc" Bradley
* Jesse Bradford as Rene Gagnon
* Jamie Bell as Ira Hayes
* Adam Beach as Mike Strank
* Barry Pepper as Sergeant Mike "Sledge" Strank
* Paul Walker as Hank Hansen
* John Benjamin Hickey as J.C. "Doc" Bradley
* Robert Patrick as Sergeant "Chucky" Snell
* Bryan Cranston as Tom Hanks
* Lucas Black as Harold "Pie" Pernell
It's important to note that the film is about the six men who raised the American flag on Mount Suribachi during the Battle of Iwo Jima, but the film focuses more on Bradley, Gagnon, and Hayes and their experiences after the battle.