Television
* The Expanse (2015-2022): As the tough and resourceful detective, Detective Miller
* Continuum (2012-2015): As Kiera Cameron's mother, Jocelyn Cameron
* Arrow (2012-2020): As Captain/Detective Janet Ryan
* Supernatural (2005-2020): In multiple roles, including Anna Milton and The Empty
* Battlestar Galactica (2004-2009): As Reena)
* Smallville (2001-2011): As Dr. Helen Bryce
* Stargate SG-1 (1997-2007): As "The Bride"
Film
* The 100 (2014): As Dr. Lorelei Tsing
* Percy Jackson & the Olympians: The Lightning Thief (2010): As The Fury
* The Colony (2013): As Jenifer
* The Butterfly Effect 2 (2006): As Melody
* A Whole New You (2012): As Sarah
* The Reunion (2009): As Jenny
Other Notable Projects
* The Listener (2009-2014): As Dr. Claire LeBlanc
* The Killing (2011-2014): As Karen
* The L Word (2004-2009): As Taffy
This is not an exhaustive list, but it highlights some of Andrea Brooks's most recognizable roles. She has also appeared in various other television series and films throughout her career.