Sasuke and Sakura: Sasuke Uchiha and Sakura Haruno are two of the main characters of the series. Sakura falls in love with Sasuke at the start of the series and spends much of it trying to win his affection. Sasuke eventually returns her feelings and they get together by the end of the series.
Shikamaru and Temari: Shikamaru Nara and Temari are introduced in the series as enemies but eventually develop a friendship and then romantic feelings for each other. They get married by the end of the series and have a son, Shikadai.
Choji and Karui: Choji Akimichi and Karui are two side characters who get together at the end of the series. They marry and have a daughter, Chocho.
Ino and Sai: Ino Yamanaka and Sai are two members of the Allied Shinobi Forces who also get together in the series. They end up getting married and have a son, Inojin.