How can you use pen drive in ps2 against memory card?

You can't directly use a pen drive in a PS2 to replace a memory card. The PS2 console doesn't have built-in support for USB drives, and there's no official way to use them for saving game progress.

Here's why:

* PS2 design: The PS2 was designed to use proprietary memory cards, not standard USB drives.

* No USB drivers: The PS2 operating system doesn't have drivers to recognize and access USB devices.

* File system incompatibility: Even if you could connect a USB drive, the PS2's internal file system wouldn't be compatible with the file system used on a pen drive.

Alternatives to using a pen drive:

* Memory cards: These are the standard way to save game progress on the PS2. You can buy them in various storage capacities.

* PS2 HDD adapter: Some third-party adapters allow you to connect a hard drive to your PS2, providing much more storage space.

* FreeMCBoot: This is a homebrew program that can be installed on a memory card and allows you to use a USB drive for storage, but it requires some technical knowledge and is not officially supported by Sony.

Important note: Using unofficial modifications like FreeMCBoot can void your PS2's warranty and may potentially damage your console if not installed correctly. Be sure to research thoroughly and proceed with caution if considering this option.