Parents:
- Mother: Mary Shakespeare (née Arden)
- Father: John Shakespeare
Spouse:
- Wife: Anne Hathaway
Children:
- Daughter: Susanna Hall (née Shakespeare)
- Daughter: Judith Quiney (née Shakespeare)
- Son: Hamnet Shakespeare (died at the age of 11)
- Son: Stillborn, unnamed sibling of Hamnet and Judith Shakespeare
Grandchildren:
- Granddaughter: Elizabeth Hall
- Granddaughter: Susanna Hall (younger)
- Granddaughter: Thomas Quiney
More Distant Relatives:
Brothers:
- Gilbert Shakespeare
- Richard Shakespeare
- Edmund Shakespeare
Sisters:
- Joan Shakespeare
- Margaret Shakespeare
- Anne Shakespeare
Nephews and Nieces:
- Several nephews and nieces from his brothers' and sisters' children. However, most of their names are now forgotten. One notable exception is Richard Quiney, son of Judith Shakespeare and Anne Hathaway's nephew, also named Thomas Quiney. Richard Quiney went on to have his father-in-law prosecuted at trial and imprisoned when they had a business and money quarrel after his father-in-law had agreed that Richard Quiney could have Shakespeare's second-best bed upon Shakespeare's death.