* 221B Baker Street: This is the iconic home of Sherlock Holmes and Dr. Watson, where much of the story takes place.
* The lodgings of Enoch Drebber: This is where the first murder occurs, setting the plot in motion.
* The London streets: Holmes and Watson roam the city, investigating clues and encountering various characters.
However, the story also includes a significant flashback to Utah, USA, where the backstory of the crime and the characters involved unfolds. This includes:
* The Mormon settlement of Salt Lake City: The story of the Mormon settlers and their revenge plot originates here.
* The desert landscapes: The journey of the Mormon emigrants, who endured hardship and persecution, takes place in the unforgiving desert.
Thus, "A Study in Scarlet" features two distinct settings: the bustling metropolis of London and the stark, desolate landscape of Utah, each playing a crucial role in the narrative and contributing to the story's complex themes of revenge, justice, and the clash between cultures.