Here's a breakdown:
* Vampire: The story revolves around vampires and their existence within a human school.
* Knight: Kaname is the main male protagonist and a pureblood vampire. He serves as the guardian of the school and protects the human students from the "night class" of vampires. He embodies a knight-like figure, upholding order and defending those under his protection.
The title aptly captures the central themes of the manga: the coexistence of vampires and humans, the battle between good and evil, and the struggle for acceptance and understanding.