Some of his notable works include:
- Poetry collections:
- "Songs of Hope" (_Anāsheed ul 'Amal_, 1997)
- "The Fragrance of the Desert" (_'Atir ul-Sahraa',_ 2001)
- "Whispers of the Soul" (_Hamsaat ul-Ruh_,_ 2005)
- "The Book of Mirrors" (_Kitāb ul-Marāyā,_ 2010)
- "The Garden of Longings" (_Jannah ul-Ashwāq_,_ 2015)
- Novels:
- "The Dove and the Falcon" (_Al-Ḥamāmah wal-Ṣaqr_,_ 2003)
- "The Sands of Time" (_Ramāl uz-Zamān_,_ 2007)
- "The Gatekeeper of Dreams" (_Ḥāris ul-Aḥlām_,_ 2011)
- "The Scent of Jasmine" (_Rayāḥat ul-Yasmeen_,_ 2015)
- "Children of the Sun" (_Abrā' ash-Shams_,_ 2019)
- Non-fiction Books:
- "The History of Dubai: A Journey Through Time" (_Tārīkh Dubayy: Riḥlah Khilāl az-Zamān_,_ 2005)
- "Emirati-Saudi Relations: A Bridge of Cooperation and Support" (_Al-'Alāqāt al-Imārātiyyah as-Sa'ūdiyyah: Jisr ut-Ta'āwun wud-Di'm_,_ 2010)
- "Reflections of a Poet: Insights and Observations on Life and Literature" (_Tafakkūrāt Shā'ir: Naẓarāt wa-Murāqabāt fī al-Ḥayāh wal-Adab_,_ 2015)
- "The Arab World in the 21st Century: Challenges and Opportunities" (_Al-Watan al-'Arabi fī al-Qarn al-Hādī wa-'l-'Ishrīn: At-Taḥaddīyāt wal-Furṣ_,_ 2020)
In addition to these, Issa Nasser Al-Ismaily has also contributed articles, op-eds, and essays to various newspapers, magazines, and journals. His work often reflects his personal experiences, observations on society, and a deep appreciation for Emirati and Arab culture.