- John Wayne as George W. McClintock
- Maureen O'Hara as Katherine "Katie" McLaughlin
- Yvonne De Carlo as Louise Warren
- Jack Kruschen as Drago
-Chill Wills as Big Jake Talon
-Walter Brennan as Bunyon "Bunny" Bartlett
-Jerry Van Dyke as Matt McClintock
-Strother Martin as Big Ben Sagebrush
-Edgar Buchanan as Judge Simpson