* The Doctor and the Priest: Conversations About Life and Death (1990)
* Caring for Self: A Healthful Path (1995)
* Every Patient Tells a Story: Medical Mysteries and the Art of Diagnosis (1999)
* Secrets in a Small Town (2002)
* It's All About the Patient: An Insider's Look at the Mistakes and Miracles of Medicine (2007)
* When Doctors Care for Doctors: The Challenges of Medical Peer Review (2010)
* Beyond Patch Adams: Humor and Healing in Healthcare (2014)
* Good Enough: A Doctor's Guide to Surviving and Thriving (2018)
Essays and Articles
* "The Doctor-Patient Relationship: A Sacred Trust" (The Journal of the American Medical Association, 1994)
* "Caring for the Caregiver" (The New England Journal of Medicine, 1995)
* "The Art of Diagnosis: Listening to the Patient" (The Lancet, 1999)
* "Medical Mistakes: What Patients Need to Know" (The New York Times, 2000)
* "The Importance of Peer Review" (The Journal of the American Medical Association, 2010)
* "Humor and Healing: The Doctor's Role" (The American Journal of Medicine, 2014)
* "The Good Enough Doctor" (The Journal of the American Medical Association, 2018)