The hormone imbalance can cause premenopausal bone loss in women. It has also been linked to the development of osteoporosis.
Estrogen/progesterone are both reproductive hormones, and so affect the reproductive system readily. The effects are early or irregular menses, polycystic ovaries or cancer of the uterus.
Foggy thinking and memory loss is another symptom that can develop from the imbalance. Mood swings, depression and insomnia may also arise.
Weight gain can occur, along with water retention, usually around the thighs, hips and stomach. Women can also become deficient in certain minerals, such as magnesium and zinc.
Estrogen dominance pumps high levels of estrogen into the body that can stay there for months. The body is tricked into thinking it's pregnant and, in this state, may become more susceptible to estrogen dominance and heart disease (because of long-term vitamin deficiency).