Here are some of the most likely candidates:
* Leonardo da Vinci's Mona Lisa: Arguably the most famous painting in the world, the Mona Lisa has been reproduced countless times in posters, prints, souvenirs, and even on everyday objects. Its iconic smile and mysterious expression have made it a global phenomenon.
* Vincent van Gogh's Starry Night: This swirling masterpiece is another highly reproduced work, often appearing on everything from coffee mugs to phone cases. Its beauty and evocative nature have made it a beloved image.
* Edvard Munch's The Scream: Known for its powerful depiction of anxiety and despair, The Scream has become a symbol of the modern condition and has been widely reproduced in popular culture.
* Michelangelo's The Creation of Adam: Part of the Sistine Chapel ceiling, this iconic image depicting God giving life to Adam is incredibly famous and has been reproduced extensively in art books, prints, and more.
Ultimately, the "most reproduced" title is subjective and depends on how you define "reproduction." It could be based on the number of physical copies made, the number of digital reproductions, or the number of times the image has been used in popular culture.
However, there's no doubt that these paintings are some of the most widely recognized and reproduced works of art in history.